The Off Topic section is not meant for discussing Cookie Clicker.
Volume 1, 5th Entry (Final)
Just damn, let's get this over with already.
mfw this cartoon is older than the protagonist. By a large margin, too. Actually, the last episode will be 10 years old in less than 7 months. Did you watch this when it was all the rage? I did, and boy let me tell you, I hadn't realized how old I am till I saw this.
You can have up to 10 (or 12 with heavenly upgrades (ascension stuff)) Wrinklers on the Big Cookie at the same time. While each Wrinkler reduces overall CpS by 5%, they each consume the Withered total. So, 10 Wrinklers equals 50% Withered CpS, and 10 Wrinklers storing 50% of your CpS each, giving an effective CpS boost of 600%. 50% CpS + 10*(50% CpS * 1.1) = 600% CpS
Grandmapocalypse is the event that begins after you purchase the One Mind upgrade. It's on the Bingo Center/Research Facility line. Since you're asking about Wrinklers, I assume you already are at least on stage 1.