Hello there !
I can't help but notice that synergies aren't actually a "meta" thing in CC. Considering that Wrinklers are the most OP thing, from early on to very-late-game, synergies, considering their horrible cost in Heavenly Chips, aren't worth it at all - the bonus they add to CpS is only useful with high tier building, which are easily reached with the first cursor upgrade. Most of the synergies are useless and too expensive, wrinklers being waaaaay more effective for HC farming.
What do you guys think ? Shall Synergies be more OP or cheaper in HC ? Imo they're kind of unbalanced...