I'm not sure whether other players have picked up on the implications of this new synergy. It connects prisms and chancemakers, but prisms are the primary beneficiaries of this synergy, gaining 5% CpS per chancemaker, while chancemakers gain only +0.1% per prism. Note that this is the first appearance of a synergy where the prisms are the primary gainer.
The upshot of this is that prisms are now a much better bargain than they used to be - better than Antimatter Condensers, and better than Chancemakers. For purposes of comparison, here are my current game stats:
Upgrades: 8 Quantity: 297 Unit CpS: 2.04 septillion Total CpS: 607 septillion Cost of next: 174 nonillion Time cost: 14 million sec
Upgrades: 9 Quantity: 300 Unit CpS: 357 septillion Total CpS: 107 octillion Cost of next: 3.27 decillion Time cost: 6.5 million sec
Upgrades: 8 Quantity: 265 Unit CpS: 31.9 septillion Total CpS: 8.47 octillion Cost of next: 304 nonillion Time cost: 9.7 million sec
Admittedly I have 9 prism upgrades against only 8 for each of the other two. However even if you double the figures for each of the other two (and therefore halve the time cost) it still shows up prisms as an incredibly good deal by comparison. Prisms are still producing nearly 90% of my CpS, even though the number of prisms is not much greater than the number of chancemakers.